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    當(dāng)前位置: 首頁(yè) » 食品資訊 » 外訊導(dǎo)讀 » 歐盟評(píng)估一種α-葡萄糖苷酶的安全性

    歐盟評(píng)估一種α-葡萄糖苷酶的安全性

    放大字體  縮小字體 時(shí)間:2022-04-29 13:59 來(lái)源:食品伙伴網(wǎng) 作者: 澤夕   
    核心提示:2022年4月28日,歐盟食品安全局就一種α-葡萄糖苷酶(α-glucosidase)的安全性評(píng)價(jià)發(fā)布意見(jiàn)。
       食品伙伴網(wǎng)訊  2022年4月28日,歐盟食品安全局就一種α-葡萄糖苷酶(α-glucosidase)的安全性評(píng)價(jià)發(fā)布意見(jiàn)。
     
      據(jù)了解,這種食品酶是由轉(zhuǎn)基因黑曲霉菌株AE-TGU生產(chǎn)的,旨在用于烘焙過(guò)程、谷物加工、釀造過(guò)程和淀粉加工中,以生產(chǎn)葡萄糖糖漿和其他淀粉水解物。
     
      經(jīng)過(guò)評(píng)估,專(zhuān)家小組認(rèn)為,在預(yù)期的使用條件下,不能排除飲食暴露引起過(guò)敏和誘發(fā)反應(yīng)的風(fēng)險(xiǎn),但這種情況發(fā)生的可能性很低。根據(jù)所提供的數(shù)據(jù),小組得出結(jié)論,該食品酶在預(yù)期的使用條件下不會(huì)引起安全隱患。部分原文報(bào)道如下:
     
      The food enzyme α-glucosidase (α-d-glucoside glucohydrolase; EC 3.2.1.20) is produced with the non-genetically modified Aspergillus niger strain AE-TGU by Amano Enzyme Inc. The food enzyme is free from viable cells of the production organism. The food enzyme is intended to be used in baking processes, cereal-based processes, brewing processes and starch processing for the production of glucose syrups and other starch hydrolysates. Since residual amounts of total organic solids (TOS) are removed by the purification steps applied during the production of glucose syrups, dietary exposure was only calculated for the remaining three food processes. based on the maximum use levels recommended, dietary exposure was estimated to be up to 0.64 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not raise a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1,062 mg TOS/kg bw per day, the highest dose tested, which when compared with the estimated dietary exposure, results in a margin of exposure of at least 1,650. A search for similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood for this to occur is considered to be low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
     
      本文由食品伙伴網(wǎng)食品資訊中心編輯,有任何疑問(wèn),請(qǐng)聯(lián)系news@foodmate.net。
    日期:2022-04-29
     
     地區(qū): 歐盟 國(guó)外
     行業(yè): 糖業(yè) 進(jìn)出口
     標(biāo)簽: 葡萄糖 歐盟食品安全局
     科普: 葡萄糖 歐盟食品安全局
     
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