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    歐盟評(píng)估轉(zhuǎn)基因地衣芽孢桿菌菌株DSM 34099生產(chǎn)的β-半乳糖苷酶的安全性

    放大字體  縮小字體 時(shí)間:2024-08-08 10:39 來源:食品伙伴網(wǎng) 作者: 澤夕   
    核心提示:2024年8月7日,歐盟食品安全局就一種β-半乳糖苷酶 (β-galactosidase)的安全性評(píng)價(jià)發(fā)布意見。
       食品伙伴網(wǎng)訊  2024年8月7日,歐盟食品安全局就一種β-半乳糖苷酶 (β-galactosidase)的安全性評(píng)價(jià)發(fā)布意見。
     
      據(jù)了解,這種食品酶是由轉(zhuǎn)基因地衣芽孢桿菌菌株DSM 34099生產(chǎn)的,旨在用于兩種食品生產(chǎn)過程。
     
      經(jīng)過評(píng)估,專家小組認(rèn)為,在預(yù)期的使用條件下,不能排除飲食暴露引起過敏反應(yīng)的風(fēng)險(xiǎn),尤其是對(duì)獼猴桃過敏的人。根據(jù)所提供的數(shù)據(jù),評(píng)估小組得出結(jié)論,這種食品酶在預(yù)期使用條件下不會(huì)引起安全問題。部分原文報(bào)道如下:
     
      The food enzyme β-galactosidase (β-d-galactoside galactohydrolase; EC 3.2.1.23) is produced with the genetically modified Bacillus licheniformis strain DSM 34099 by Kerry Group Services International, Ltd. (KGSI). The genetic modifications do not give rise to safety concerns. The food enzyme is free from viable cells of the production organism and its DNA. The production strain met the requirements for the qualified presumption of safety (QPS) approach. The food enzyme is intended to be used in two food manufacturing processes. Dietary exposure was estimated to be up to 7.263 mg total organic solids/kg body weight per day in European populations. Given the QPS status of the production strain and the absence of concerns resulting from the food enzyme manufacturing process, toxicity tests, other than an assessment of allergenicity, were considered unnecessary by the Panel. A search for the identity of the amino acid sequence of the food enzyme to known allergens was made and one match with a food allergen from kiwi fruit was found. The Panel considered that a risk of allergic reactions upon dietary exposure to this food enzyme, particularly in individuals sensitised to kiwi fruit, cannot be excluded. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use.
     
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    日期:2024-08-08
     
     
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