食品伙伴網(wǎng)訊  2020年2月24日，據(jù)歐盟食品安全局（EFSA）消息，應(yīng)歐盟委員會(huì)要求，歐盟動(dòng)物飼料添加劑和產(chǎn)品（FEEDAP）研究小組就一種L-色氨酸（L-tryptophan）作為所有動(dòng)物品種的飼料和飲用水的營(yíng)養(yǎng)添加劑發(fā)表科學(xué)意見(jiàn)。

 

　　據(jù)了解，這種L-色氨酸是由轉(zhuǎn)基因大腸桿菌菌株CGMCC 7.267發(fā)酵產(chǎn)生。經(jīng)過(guò)評(píng)估，小組認(rèn)為，這種添加劑對(duì)消費(fèi)者和環(huán)境是安全的。由于缺乏數(shù)據(jù)，專(zhuān)家小組無(wú)法得出添加劑對(duì)皮膚和眼睛有刺激性或?qū)ζつw有致敏性的結(jié)論。部分原文報(bào)道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed （FEEDAP） was asked to deliver a scientific opinion on l‐tryptophan produced by fermentation with a genetically modified strain of Escherichia coli CGMCC 7.267 when used as a nutritional additive in feed and water for drinking for all animal species and categories. The production strain E. coli CGMCC 7.267 is safe for the production of l‐tryptophan. No viable cells or DNA of the production strain were detected in the additive under assessment. The use of l‐tryptophan produced using E. coli CGMCC 7.267 in supplementing feed to compensate for tryptophan deficiency in feedingstuffs is safe for non‐ruminant target species. However, excess doses would create amino acid imbalances with negative consequences on animal performance. The use of unprotected l‐tryptophan in feed poses safety concerns for ruminants. The use of l‐tryptophan produced by fermentation with E. coli CGMCC 7.267 in animal nutrition is considered safe for the consumers and for the environment. The endotoxin activity in the product and its dusting potential indicate an inhalation risk for the user. In the absence of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and eyes or to be a skin sensitiser. The additive l‐tryptophan produced using E. coli CGMCC 7.267 is regarded as an effective source of the amino acid l‐tryptophan. In order to be as efficacious in ruminants as in non‐ruminants, it should be protected from ruminal degradation.

 

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