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    歐盟評估谷氨酸棒桿菌KCCM 80346生產(chǎn)的L-色氨酸作為所有動物飼料添加劑的安全性和有效性
    日期:2025-04-07  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2025年4月2日,據(jù)歐盟食品安全局EFSA)消息,應歐盟委員會要求,歐盟動物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就谷氨酸棒桿菌KCCM 80346發(fā)酵生產(chǎn)的L-色氨酸(L‐tryptophan)作為所有動物飼料添加劑的安全性和有效性發(fā)表科學意見。
     
      經(jīng)過評估,專家小組認為該添加劑對目標物種、消費者和環(huán)境是安全的。評估中的添加劑被認為是所有非反芻動物物種氨基酸L-色氨酸的有效來源。為了使補充的L-色氨酸對反芻動物和非反芻動物同樣有效,需要防止其在瘤胃中降解。部分原文報道如下:
     
      Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of the feed additive consisting of l-tryptophan produced by fermentation with a genetically modified strain of Corynebacterium glutamicum (KCCM 80346) when used as a nutritional additive in feed and water for drinking for all animal species and categories. Viable cells of the production strain and its DNA were not detected in the additive. l-Tryptophan manufactured by fermentation using C. glutamicum KCCM 80346 does not give rise to any safety concern with regard to the genetic modification of the production strain. The use of l-tryptophan (≥ 98%) produced with C. glutamicum KCCM 80346 to supplement feed is safe for non-ruminant species. There may be a risk for an increased production of toxic metabolites when unprotected tryptophan is used in ruminants. The FEEDAP Panel has concerns on the use of l-tryptophan in water for drinking. The use of l-tryptophan produced with C. glutamicum KCCM 80346 in animal nutrition raises no safety concerns to consumers of products from animals receiving the additive and to the environment. l-tryptophan produced with C. glutamicum KCCM 80346 is not irritant to the eyes and skin, and it is not a skin sensitiser. The additive l-tryptophan is regarded as an effective source of the amino acid l-tryptophan for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.
     
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