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    歐盟評估非轉(zhuǎn)基因Limtongozyma cylindracea菌株AE-LAYH (B)生產(chǎn)的三酰甘油脂肪酶的安全性
    日期:2024-10-17  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2024年10月16日,歐盟食品安全局就一種食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性評價發(fā)布意見。
      
      據(jù)了解,這種食品酶是由非轉(zhuǎn)基因Limtongozyma cylindracea菌株AE-LAYH (B)生產(chǎn)的,旨在用于6種食品生產(chǎn)過程。
      
      經(jīng)過評估,專家小組認為,在預期的使用條件下,不能排除通過飲食接觸引起過敏反應的風險,特別是對蜂蜜過敏的人,但這種情況發(fā)生的可能性很低。根據(jù)所提供的數(shù)據(jù),小組得出結(jié)論,該食品酶在預期的使用條件下不會引起安全問題。部分原文報道如下:
      
      The food enzyme, a triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.3), is produced with the non-genetically modified Limtongozyma cylindracea strain AE-LAYH (B) by Amano Enzyme Inc. It is intended to be used in six food manufacturing processes. Since residual amounts of food enzyme–total organic solids (TOS) are removed in one process, dietary exposure was calculated only for the remaining five food manufacturing processes. It was estimated to be up to 0.315 mg TOS/kg body weight (bw) per day in European populations. As the production strain qualifies for the quality presumption of safety (QPS) approach of safety assessment and no issue of concern arising from the production process of the food enzyme were identified, the Panel considered that no toxicological studies other than the assessment of allergenicity were necessary. A homology search for the amino acid sequence of the food enzyme to those of known allergens was made and one match with a honeybee venom allergen was found. The Panel considered that a risk of allergic reactions by dietary exposure, particularly in individuals allergic to honey, cannot be excluded, but is considered to be low. based on the data provided, the QPS status of the production strain and the absence of issues of concern arising from the food enzyme manufacturing process, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
      
      本文由食品伙伴網(wǎng)食品資訊中心編輯,供網(wǎng)友參考,有任何疑問,請聯(lián)系news@foodmate.net。
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