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    歐盟評(píng)估非轉(zhuǎn)基因解淀粉芽孢桿菌菌株NZYM-WR生產(chǎn)的α-淀粉酶的安全性
    日期:2023-12-08  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2023年12月7日,歐盟食品安全局就一種α-淀粉酶(α-amylase)的安全性評(píng)價(jià)發(fā)布意見。
     
      據(jù)了解,這種食品酶是由非轉(zhuǎn)基因淀粉芽孢桿菌菌株NZYM-WR生產(chǎn)的,旨在用于九種食品生產(chǎn)過程:加工谷物和其他谷物以生產(chǎn)焙烤產(chǎn)品、非焙烤的谷物基產(chǎn)品、葡萄糖漿和其他淀粉水解產(chǎn)物、蒸餾酒精和釀造產(chǎn)品;精制糖和未精制糖的生產(chǎn),基于植物的牛奶類似物和奶制品的生產(chǎn);加工水果和蔬菜以生產(chǎn)果汁和果汁以外的水果和蔬菜產(chǎn)品。
     
      經(jīng)過評(píng)估,專家小組認(rèn)為,在預(yù)期的使用條件下(蒸餾酒精生產(chǎn)除外),不能排除飲食暴露引起過敏反應(yīng)的風(fēng)險(xiǎn),但這種可能性被認(rèn)為很低。根據(jù)所提供的數(shù)據(jù),評(píng)估小組得出結(jié)論,這種食品酶在預(yù)期使用條件下不會(huì)引起安全問題。部分原文報(bào)道如下:
     
      The food enzyme α-amylase (4-α-d-glucan glucanohydrolase; EC 3.2.1.1) is produced with the non-genetically modified Bacillus amyloliquefaciens strain NZYM-WR by Novozymes A/S. The production strain met the requirements for the qualified presumption of safety (QPS) approach. The food enzyme is intended to be used in nine food manufacturing processes: processing of cereals and other grains for the production of baked products, cereal-based products other than baked, glucose syrups and other starch hydrolysates, distilled alcohol and brewed products; production of refined and unrefined sugar, production of plant-based analogues of milk and milk products; processing of fruits and vegetables for the production of juices and fruit and vegetable products other than juices. Since residual amounts of total organic solids (TOS) are removed during two processes, a dietary exposure was calculated only for the remaining seven food manufacturing processes. Exposure was estimated to be up to 0.450 mg TOS/kg body weight per day in European populations. As the production strain qualified for the QPS approach and no issues of concern arose from the production process of the food enzyme, the Panel considered that toxicological studies were unnecessary. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and one match with a respiratory allergen was found. The Panel considered that the risk of allergic reactions upon dietary exposure to this food enzyme cannot be excluded (except for distilled alcohol production), but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
     
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