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    歐盟評估谷氨酸棒桿菌CGMCC 7.453生產(chǎn)的L-賴氨酸鹽酸鹽作為所有動物飼料添加劑的安全性和有效性
    日期:2025-04-08  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2025年4月3日,據(jù)歐盟食品安全局EFSA)消息,應(yīng)歐盟委員會要求,歐盟動物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就谷氨酸棒桿菌CGMCC 7.453發(fā)酵生產(chǎn)的L-賴氨酸鹽酸鹽(l-lysine monohydrochloride)作為所有動物飼料添加劑的安全性和有效性發(fā)表科學(xué)意見。
     
      經(jīng)過評估,專家小組認(rèn)為該添加劑對目標(biāo)物種、消費者和環(huán)境是安全的。評估中的添加劑被認(rèn)為是所有非反芻動物物種氨基酸L-賴氨酸的有效來源。為了使補充的L-賴氨酸對反芻動物和非反芻動物同樣有效,需要防止其在瘤胃中降解。部分原文報道如下:
     
      Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-lysine monohydrochloride produced by fermentation with a genetically modified strain of Corynebacterium glutamicum (CGMCC 7.453) as nutritional feed additive for all animal species. Neither viable cells nor recombinant DNA of the production strain were detected in the final product. Therefore, the FEEDAP Panel concluded that the additive does not pose any safety concern regarding the production strain. The FEEDAP Panel concluded that the use of l-lysine HCl produced by fermentation with the strain C. glutamicum CGMCC 7.453 is safe for the target species when administered via feed. However, the FEEDAP Panel expressed concerns on the use of l-lysine HCl in water for drinking. The Panel concluded that the use of l-lysine HCl produced by fermentation with C. glutamicum CGMCC 7.453 in animal nutrition is considered safe for the consumers and for the environment. With regards user safety, the additive should be considered irritant to skin, eyes and the respiratory tract. Any exposure to the additive is a risk. l-Lysine HCl is considered as efficacious source of the essential amino acid l-lysine for non-ruminant animal species. For the supplemental l-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen.
     
      本文由食品伙伴網(wǎng)食品資訊中心編輯,有任何疑問,請聯(lián)系news@foodmate.net。
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