經(jīng)過評估,專家小組認為該添加劑對目標物種、消費者和環(huán)境是安全的。評估中的添加劑被認為是所有非反芻動物物種氨基酸L-纈氨酸的有效來源。為了使補充的L-纈氨酸對反芻動物和非反芻動物同樣有效,需要防止其在瘤胃中降解。部分原文報道如下:
Following a request from the European Commission, the European Food Safety Authority (EFSA) was asked to deliver a scientific opinion on the safety and efficacy of l-valine produced with a genetically modified strain of Corynebacterium glutamicum (KCCM 80365) when used as a nutritional additive in feed and water for drinking for all animal species and categories. l-Valine manufactured by fermentation using C. glutamicum KCCM 80365 does not give rise to any safety concern regarding the genetic modifications of the production strain. No viable cells or DNA of the production strain were detected in the final product. The use of l-valine produced with C. glutamicum KCCM 80365 in feed is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the species. The FEEDAP Panel has concerns on the use of l-valine in water for drinking. The use of l-valine produced by fermentation with C. glutamicum KCCM 80365 in animal nutrition is considered safe for the consumers and for the environment. l-Valine produced with C. glutamicum KCCM 80365 is not irritant to skin and eyes, nor considered a skin sensitiser. The additive l-valine is regarded as an effective source of the amino acid l-valine for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.
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