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    歐盟評(píng)估轉(zhuǎn)基因黑曲霉菌株XEA生產(chǎn)的內(nèi)切-1,4-β-木聚糖酶的安全性
    日期:2025-03-31  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2025年3月28日,歐盟食品安全局就一種食品酶內(nèi)切-1,4-β-木聚糖酶(endo-1,4-β-xylanase)的安全性評(píng)價(jià)發(fā)布意見。
     
      據(jù)了解,這種食品酶是由轉(zhuǎn)基因黑曲霉菌株XEA生產(chǎn)的,旨在用于6種食品制造過程。
     
      根據(jù)新的數(shù)據(jù)、修訂的暴露限度和以前的評(píng)估,小組得出結(jié)論,該食品酶在預(yù)期的使用條件下不會(huì)引起安全問題。部分原文報(bào)道如下:
     
      The food enzyme endo-1,4-β-xylanase (4-β-d-xylan xylanohydrolase, EC 3.2.1.8) is produced with the genetically modified Aspergillus niger strain XEA by DSM Food Specialties B.V. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in two food manufacturing processes. Subsequently, the applicant has requested to extend its use to include four additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of six food manufacturing processes. The dietary exposure was calculated to be up to 0.316 mg total organic solids (TOS)/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1852 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 5861. based on the new data, the revised margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
     
      本文由食品伙伴網(wǎng)食品資訊中心編輯,供網(wǎng)友參考,有任何疑問,請(qǐng)聯(lián)系news@foodmate.net。
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