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    歐盟評估擴展使用轉(zhuǎn)基因里氏木霉菌株 RF10625生產(chǎn)的三酰甘油脂肪酶的安全性
    日期:2025-03-03  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2025年2月28日,歐盟食品安全局就一種食品酶三酰甘油脂肪酶(triacylglycerol lipase)的安全性評價發(fā)布意見。
      
      據(jù)了解,這種食品酶是由轉(zhuǎn)基因里氏木霉菌株 RF10625生產(chǎn)的,旨在用于五種食品生產(chǎn)過程。
      
      經(jīng)過評估,專家小組得出結(jié)論,這種食品酶在預(yù)期使用條件下不會引起安全問題。部分原文報道如下:
      
      The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.3) is produced with the genetically modified Trichoderma reesei strain RF10625 by AB Enzymes GmbH. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in two food manufacturing processes. Subsequently, the applicant has requested to extend its use to include three additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of five food manufacturing processes. As the food enzyme–total organic solids (TOS) are removed from the final foods in one food manufacturing process, the dietary exposure to the food enzyme–TOS was estimated only for the remaining four processes. It was calculated to be up to 0.197 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1000 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 5076. based on the new data, the revised margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
      
      本文由食品伙伴網(wǎng)食品資訊中心編輯,供網(wǎng)友參考,有任何疑問,請聯(lián)系news@foodmate.net。
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