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    歐盟評估一種由內(nèi)切-1,4-β-木聚糖酶、內(nèi)切-1,4-β-葡聚糖酶和木葡聚糖特異性內(nèi)切-β-1,4-葡聚糖酶組成的飼料添加劑對所有豬科動物的安全性和有效性
    日期:2024-03-08  來源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2024年3月6日,據(jù)歐盟食品安全局EFSA)消息,應(yīng)歐盟委員會要求,歐盟動物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就一種由內(nèi)切-1,4-β-木聚糖酶(endo-1,4-beta-xylanase)、內(nèi)切-1,4-β-葡聚糖酶(endo-1,4-beta-glucanase)和木葡聚糖特異性內(nèi)切-β-1,4-葡聚糖酶(xyloglucan-specific endo-beta-1,4-glucanase)組成的飼料添加劑對所有豬科動物的安全性和有效性發(fā)表科學(xué)意見。
     
      據(jù)了解,添加劑中的三種酶是由桔綠木霉DSM 33578生產(chǎn)的。部分原文報道如下:
     
      Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Huvezym® neXo 100 G/L, a product containing endo-1,4-β-xylanase, endo-1,4-β-glucanase and xyloglucan-specific-endo-β-1,4-glucanase activities produced by a non-genetically modified strain of Trichoderma citrinoviride (DSM 33578), as a zootechnical additive for all Suidae. The applicant provided information confirming the taxonomic identification of the production strain. The batches used for the characterisation of the final formulations showed compliance with the minimum specifications of the additive in terms of enzyme activities (> 15,000 EPU, > 1000 CU, > 1000 XGU per g) but not for the ratio of the enzymes, which is lower (ca. 7:1:1) than the ones specified (15:1:1). The Panel could not conclude on the representativeness of the test item used in the toxicological and tolerance studies with respect to the final formulations. Therefore, the conclusions are limited to the product with a minimum enzyme activity of 15,000 EPU, 1000 CU, 1000 XGU per g and a xylanase:glucanase:xyloglucanase ratio of 15:1:1. The Panel concluded that the additive is safe for the target species, consumers and the environment. Huvezym® neXo 100 G is not an irritant to the skin and eyes but should be considered a skin sensitiser. Huvezym® neXo 100 L is neither an irritant to the skin and eyes nor a skin sensitiser. Due to the proteinaceous nature of the active substances, the additive is considered a respiratory sensitiser. The additive has the potential to be efficacious in all reproductive Suidae at the minimum proposed use level. Owing to the lack of sufficient data, the Panel could not conclude on the efficacy of the additive for Suidae for fattening or reared for reproduction.
     
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