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    歐盟評(píng)估由濃縮液態(tài)L-賴氨酸、L-賴氨酸鹽酸鹽和濃縮液態(tài)L-賴氨酸鹽酸鹽組成的飼料添加劑對(duì)所有動(dòng)物的安全性和有效性
    日期:2022-10-26  來(lái)源:食品伙伴網(wǎng)
       食品伙伴網(wǎng)訊  2022年10月25日,據(jù)歐盟食品安全局EFSA)消息,應(yīng)歐盟委員會(huì)要求,歐盟動(dòng)物飼料添加劑和產(chǎn)品(FEEDAP)研究小組就由濃縮液態(tài)L-賴氨酸、L-賴氨酸鹽酸鹽和濃縮液態(tài)L-賴氨酸鹽酸鹽組成的飼料添加劑對(duì)所有動(dòng)物的安全性和有效性發(fā)表科學(xué)意見(jiàn)。
     
      據(jù)了解,該添加劑是由大腸桿菌NITE BP-02917生產(chǎn)的。經(jīng)過(guò)評(píng)估,專家小組認(rèn)為該添加劑對(duì)目標(biāo)物種、消費(fèi)者和環(huán)境都是安全的。評(píng)估中的添加劑被認(rèn)為是非反芻動(dòng)物物種必需氨基酸L-賴氨酸的有效來(lái)源。為了使補(bǔ)充的L-賴氨酸對(duì)反芻動(dòng)物和非反芻動(dòng)物同樣有效,需要防止其在瘤胃中降解。在建議的使用條件下,這三種形式的添加劑也被認(rèn)為是有效的飼料調(diào)味化合物。部分原文報(bào)道如下:
     
      Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of concentrated liquid l-lysine, l-lysine monohydrochloride and concentrated liquid l-lysine monohydrochloride produced by Escherichia coli NITE BP-02917 as nutritional and as sensory (flavouring compound) feed additives for all animal species. The production strain did not carry ■■■■■ antimicrobial resistance genes and no viable cells of the production strain were detected in the final products. ■■■■■ However, since no sequences of concern remained in the production strain, the potential presence of that DNA did not raise safety concerns. The use of the three forms of l-lysine produced by E. coli NITE BP-02917 in supplementing feed to compensate for l-lysine deficiency in feedingstuffs was safe for the target species. This conclusion would also cover the use as a sensory additive. The FEEDAP Panel identified risks of nutritional imbalances and hygienic concerns for amino acids when administered simultaneously in feed and in water for drinking. The use of the three forms of l-lysine produced by E. coli NITE BP-02917 in animal nutrition was considered safe for the consumers and for the environment. Concentrated liquid l-lysine, l-lysine HCl and concentrated liquid l-lysine HCl were not considered to have the potential to cause respiratory toxicity, or skin sensitisation. l-Lysine HCl and concentrated liquid l-lysine HCl were not considered skin and eye irritants. Concentrated liquid l-lysine, due to its high pH, might be corrosive for skin and eyes. The three forms were considered an efficacious source of the essential amino acid l-lysine for non-ruminant animal species. For the supplemental l-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen. The three forms of the additive were also considered efficacious as feed flavouring compounds under the proposed conditions of use.
     
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